Efficacia degli approcci comportamentali della Psychologically Informed Physical Therapy (PIPT) in soggetti con Low Back Pain: una revisione sistematica

Effectiveness of Psychologically Informed Physical Therapy (PIPT) behavioral approaches in subjects with Low Back Pain: a systematic review

Autori

Cappelletti Sonia [Università degli Studi di Firenze, Firenze, Italia]

Di Bari Mauro [Università degli Studi di Firenze, Firenze, Italia]

Borghi Sara [Università degli Studi di Firenze, Firenze, Italia]

Introduction

Low Back Pain (LBP) is the most common and important clinical, social
and economic problem of all musculoskeletal disorders. Several factors, including
biological, psychological, social, genetic, may contribute to the persistence of pain and
disability of LBP. NICE guidelines promote the use of conservative treatment that
incorporates pain self-management, therapeutic exercise, manual therapy.
Psychologically Informed Physical Therapy (PIPT) represents a multimodal
rehabilitation approach to treating pain that incorporates behavioral strategies from the
mental health realm into the physical therapist’s practice. The aim of this study is to
investigate the effectiveness of behavioral PIPT approaches in patients with
musculoskeletal LBP.

Methods

A systematic review was conducted in PubMed, Embase, Cochrane Library,
CINAHL, Scopus, PEDro, PsycInfo and Web of Science. RCTs that met the eligibility
criteria of the present research were included. The studies were assessed by blinded
reviewers using standardized tables. The assessment of the methodological quality of the
studies was carried out using the Risk of Bias 2.0 tool.

Results

11 RCTs that met the inclusion/exclusion criteria were included. 8 studies had a
high risk of bias, 3 studies had a moderate risk of bias. The sample size of the included
studies varies from 30 participants to 248. Only one RCT investigates subacute LBP, the
remaining trials include only patients with chronic LBP. The results showed that
behavioral PIPT approaches, associated or not with other interventions, are effective
compared to active or passive control groups in the outcome of fear-avoidance, anxiety
and depression and in the quality of life both post-intervention and to follow-up.

Discussion and Conclusion

The results of this systematic review suggest that there is limited and
inconsistent evidence on the effectiveness of behavioral PIPT interventions in patients
with LBP. Further research will be necessary to produce clinical trials with
greater methodological quality and standardization of procedures.

REFERENCES

1. Burton AK, Balagué F, Cardon G, Eriksen HR, Henrotin Y, Lahad A, et al. Chapter 2. European guidelines for prevention in low back pain : November 2004. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc. marzo 2006;15 Suppl 2(Suppl 2):S136-168.

2. Violante FS, Mattioli S, Bonfiglioli R. Low-back pain. Handb Clin Neurol. 2015;131:397–410.
3. Halonen JI, Shiri R, Magnusson Hanson LL, Lallukka T. Risk and Prognostic Factors of Low Back Pain: Repeated Population-based Cohort Study in Sweden. Spine. 1 settembre 2019;44(17):1248–55.

4. Blyth FM, Briggs AM, Schneider CH, Hoy DG, March LM. The Global Burden of Musculoskeletal Pain-Where to From Here? Am J Public Health. gennaio 2019;109(1):35–40.
5. GBD 2021 Low Back Pain Collaborators. Global, regional, and national burden of low back pain, 1990-2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. giugno 2023;5(6):e316–29.

6. Artus M, Holt TA, Rees J. The painful shoulder: an update on assessment, treatment, and referral. Br J Gen Pract. settembre 2014;64(626):e593–5.
7. Klintberg IH, Cools AMJ, Holmgren TM, Holzhausen ACG, Johansson K, Maenhout AG, et al. Consensus for physiotherapy for shoulder pain. Int Orthop. aprile 2015;39(4):715–20.

8. Adamson J, Ebrahim S, Dieppe P, Hunt K. Prevalence and risk factors for joint pain among men and women in the West of Scotland Twenty‐07 study. Ann Rheum Dis. aprile 2006;65(4):520–4.
9. GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Lond Engl. 17 ottobre 2020;396(10258):1204–22.

10. Overview | Low back pain and sciatica in over 16s: assessment and management | Guidance | NICE [ Internet ]. NICE; 2016 [citato 3 dicembre 2023]. Disponibile su: https://www.nice.org.uk/guidance/ng59
11. Main CJ, George SZ. Psychologically informed practice for management of low back pain: future directions in practice and research. Phys Ther. maggio 2011;91(5):820–4.

12. Coronado RA, Brintz CE, McKernan LC, Master H, Motzny N, Silva FM, et al. Psychologically informed physical therapy for musculoskeletal pain: current approaches, implications, and future directions from recent randomized trials. Pain Rep. 2020;5(5):e847.

13. O’Sullivan PB, Caneiro JP, O’Keeffe M, Smith A, Dankaerts W, Fersum K, et al. Cognitive Functional Therapy: An Integrated Behavioral Approach for the Targeted Management of Disabling Low Back Pain. Phys Ther. 1 maggio 2018;98(5):408–23.

14. Pincus T, Kent P, Bronfort G, Loisel P, Pransky G, Hartvigsen J. Twenty-five years with the biopsychosocial model of low back pain-is it time to celebrate? A report from the twelfth international forum for primary care research on low back pain. Spine. 15 novembre 2013;38(24):2118–23.

15. Arnold LM, Hudson JI, Keck PE, Auchenbach MB, Javaras KN, Hess EV. Comorbidity of fibromyalgia and psychiatric disorders. J Clin Psychiatry. agosto 2006;67(8):1219–25.
16. Generaal E, Vogelzangs N, Penninx BWJH, Dekker J. Insomnia, Sleep Duration, Depressive Symptoms, and the Onset of Chronic Multisite Musculoskeletal Pain. Sleep. 1 gennaio 2017;40(1).

17. Leung L. Pain catastrophizing: an updated review. Indian J Psychol Med. luglio 2012;34(3):204–17.
18. Eisenberger NI. The pain of social disconnection: examining the shared neural underpinnings of physical and social pain. Nat Rev Neurosci. 3 maggio 2012;13(6):421–34.

19. Sturgeon JA, Dixon EA, Darnall BD, Mackey SC. Contributions of physical function and satisfaction with social roles to emotional distress in chronic pain: a Collaborative Health Outcomes Information Registry (CHOIR) study. Pain. dicembre 2015;156(12):2627–33.

20. Ballengee LA, Zullig LL, George SZ. Implementation of Psychologically Informed Physical Therapy for Low Back Pain: Where Do We Stand, Where Do We Go? J Pain Res. 2021;14:3747–57.
21. Wood L, Hendrick PA. A systematic review and meta-analysis of pain neuroscience education for chronic low back pain: Short-and long-term outcomes of pain and disability. Eur J Pain Lond Engl. febbraio 2019;23(2):234–49.

22. Ma X, Chen R, Li W, Huang P. A systematic review and meta-analysis of pain neuroscience education for chronic low back pain: short-term outcomes of pain and disability. Physiother Theory Pract. 3 luglio 2023;1–20.
23. Shin S, Kim H. Carryover Effects of Pain Neuroscience Education on Patients with Chronic Lower Back Pain: A Systematic Review and Meta-Analysis. Med Kaunas Lith. 7 luglio 2023;59(7):1268.

24. Devonshire JJ, Wewege MA, Hansford HJ, Odemis HA, Wand BM, Jones MD, et al. Effectiveness of Cognitive Functional Therapy for Reducing Pain and Disability in Chronic Low Back Pain: A Systematic Review and Meta-analysis. J Orthop Sports Phys Ther. maggio 2023;53(5):244–85.

25. Miki T, Kondo Y, Kurakata H, Buzasi E, Takebayashi T, Takasaki H. The effect of cognitive functional therapy for chronic nonspecific low back pain: a systematic review and meta-analysis. Biopsychosoc Med. 21 maggio 2022;16(1):12.
26. Hall A, Richmond H, Copsey B, Hansen Z, Williamson E, Jones G, et al. Physiotherapist-delivered cognitive-behavioural interventions are effective for low back pain, but can they be replicated in clinical practice? A systematic review. Disabil Rehabil. gennaio 2018;40(1):1–9.

27. Yang J, Lo WLA, Zheng F, Cheng X, Yu Q, Wang C. Evaluation of Cognitive Behavioral Therapy on Improving Pain, Fear Avoidance, and Self-Efficacy in Patients

with Chronic Low Back Pain: A Systematic Review and Meta-Analysis. Pain Res Manag. 2022;2022:4276175.
28. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 29 marzo 2021;372:n71.
29. Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Rev. 5 dicembre 2016;5(1):210.
30. Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 28 agosto 2019;366:l4898.
31. McGuinness LA, Higgins JPT. Risk-of-bias VISualization (robvis): An R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods. gennaio 2021;12(1):55–61.
32. Storheim K, Brox JI, Holm I, Koller AK, Bø K. Intensive group training versus cognitive intervention in sub-acute low back pain: short-term results of a single-blind randomized controlled trial. J Rehabil Med. maggio 2003;35(3):132–40.
33. Vibe Fersum K, O’Sullivan P, Skouen JS, Smith A, Kvåle A. Efficacy of classification-based cognitive functional therapy in patients with non-specific chronic low back pain: a randomized controlled trial. Eur J Pain Lond Engl. luglio 2013;17(6):916–28.
34. Khan M, Akhter S, Soomro RR, Ali SS. The effectiveness of Cognitive Behavioral Therapy (CBT) with general exercises versus general exercises alone in the management of chronic low back pain. Pak J Pharm Sci. luglio 2014;27(4 Suppl):1113– 6.
35. Magalhães MO, Muzi LH, Comachio J, Burke TN, Renovato França FJ, Vidal Ramos LA, et al. The short-term effects of graded activity versus physiotherapy in patients with chronic low back pain: A randomized controlled trial. Man Ther. agosto 2015;20(4):603–9.
36. Aliyu FY, Wasiu AA, Bello B. Effects of a combined lumbar stabilization exercise and cognitive behavioral therapy on selected variables of individuals with non- specific low back pain: A randomized clinical trial. Fisioterapia. 1 settembre 2018;40(5):257–64.
37. Vibe Fersum K, Smith A, Kvåle A, Skouen JS, O’Sullivan P. Cognitive functional therapy in patients with non-specific chronic low back pain-a randomized controlled trial 3-year follow-up. Eur J Pain Lond Engl. settembre 2019;23(8):1416–24. 38. Godfrey E, Wileman V, Galea Holmes M, McCracken LM, Norton S, Moss- Morris R, et al. Physical Therapy Informed by Acceptance and Commitment Therapy (PACT) Versus Usual Care Physical Therapy for Adults With Chronic Low Back Pain: A Randomized Controlled Trial. J Pain. 2020;21(1–2):71–81.
39. Khodadad B, Letafatkar A, Hadadnezhad M, Shojaedin S. Comparing the Effectiveness of Cognitive Functional Treatment and Lumbar Stabilization Treatment on Pain and Movement Control in Patients With Low Back Pain. Sports Health. 2020;12(3):289–95.
40. Bagheri R, Hedayati R, Ehsani F, Hemati-Boruojeni N, Abri A, Taghizadeh Delkhosh C. Cognitive Behavioral Therapy With Stabilization Exercises Affects Transverse Abdominis Muscle Thickness in Patients With Chronic Low Back Pain: A Double-Blinded Randomized Trial Study. J Manipulative Physiol Ther. giugno 2020;43(5):418–28.

41. Akodu AK, Akindutire OM. The effect of stabilization exercise on pain-related disability, sleep disturbance, and psychological status of patients with non-specific chronic low back pain. Korean J Pain. luglio 2018;31(3):199–205.
42. Aneis M, Shaker H, Fahmy E, Yousef K. EFECT OF COGNITIVE BEHAVIOR THERAPY IN PATIENTS WITH CHRONIC NONSPECIFIC LOW BACK PAIN. Türk Fiz Ve Rehabil DergisiTurkish J Physiother Rehabil. 10 luglio 2021;32.

43. Cherkin DC, Sherman KJ, Balderson BH, Cook AJ, Anderson ML, Hawkes RJ, et al. Effect of Mindfulness-Based Stress Reduction vs Cognitive Behavioral Therapy or Usual Care on Back Pain and Functional Limitations in Adults With Chronic Low Back Pain: A Randomized Clinical Trial. JAMA. 22 marzo 2016;315(12):1240–9.

44. Hadley G, Novitch MB. CBT and CFT for Chronic Pain. Curr Pain Headache Rep. 1 aprile 2021;25(5):35.
45. O’Keeffe M, O’Sullivan P, Purtill H, Bargary N, O’Sullivan K. Cognitive functional therapy compared with a group-based exercise and education intervention for chronic low back pain: a multicentre randomised controlled trial (RCT). Br J Sports Med. luglio 2020;54(13):782–9.

46. Baez S, Hoch MC, Hoch JM. Evaluation of Cognitive Behavioral Interventions and Psychoeducation Implemented by Rehabilitation Specialists to Treat Fear- Avoidance Beliefs in Patients With Low Back Pain: A Systematic Review. Arch Phys Med Rehabil. 1 novembre 2018;99(11):2287–98.

47. Hughes LS, Clark J, Colclough JA, Dale E, McMillan D. Acceptance and Commitment Therapy (ACT) for Chronic Pain: A Systematic Review and Meta- Analyses. Clin J Pain. giugno 2017;33(6):552.
48. Sanabria-Mazo JP, Colomer-Carbonell A, Borràs X, Castaño-Asins JR, McCracken LM, Montero-Marin J, et al. Efficacy of Videoconference Group Acceptance and Commitment Therapy (ACT) and Behavioral Activation Therapy for Depression (BATD) for Chronic Low Back Pain (CLBP) Plus Comorbid Depressive Symptoms: A Randomized Controlled Trial (IMPACT Study). J Pain. 1 agosto 2023;24(8):1522–40.

49. Vlaeyen JW, Haazen IW, Schuerman JA, Kole-Snijders AM, van Eek H. Behavioural rehabilitation of chronic low back pain: comparison of an operant treatment, an operant-cognitive treatment and an operant-respondent treatment. Br J Clin Psychol. febbraio 1995;34(1):95–118.

50. Woods MP, Asmundson GJG. Evaluating the efficacy of graded in vivo exposure for the treatment of fear in patients with chronic back pain: a randomized controlled clinical trial. Pain. giugno 2008;136(3):271–80.